Figure 11­26
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Pacinian corpuscles are encapsulated sensory nerve endings located in the dermis of the skin. These receptors are
Holdings,
found in the deeper layers of the dermis and sense pressure and vibrations. In addition to the skin, they are also
located in joint capsules, ligaments, serous membranes, and mesenteries.
LLC.
In cross-section, the three Pacinian corpuscles in this micrograph resemble the cut surface of an onion. Within the
Not
connective tissue capsule, flattened cells and delicate connective tissue fibrils are wrapped concentrically around an
to
unmyelinated axon (arrowhead).
be
redistributed
The thick connective tissue capsule of the Pacinian corpuscle is shown at the arrows. Concentric lamellae of flat,
fibroblast-like cells and collagen fibrils encircle an unmyelinated axon. The lamellae are packed more closely togeth-
er near the center. The axon is myelinated as it leaves the capsule. Between the cells and fibrils in the corpuscle is
or
interstitial fluid. Vibratory stimulus or pressure distorts the corpuscle and generates an action potential in the nerve.
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in
any
way
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627

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