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Peripheral T-Cell Lymphomas: Example 5A This lymphoma was also present in the bone marrow. Here in a lymph node it has a mixture of small and large cells. Some of the large cells show marked atypia including multinuclearity. Many scattered epithelioid histiocytes accompany the malignant T-cells, so that this case could be described as Lennert's lymphoma (a designation not used in the WHO classification). A lymph node with an infiltrate causing mostly pale, diffuse areas. The pallor is due to the abundant cytoplasm of the T-cells and also the interspersed epithelioid histiocytes. A range of small and large atypical cells is seen here in addition to histiocytes. Uh-oh, be careful! It looks like a Reed-Sternberg cell, but this isn't Hodgkin's disease. Table of Contents